Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-3-carboxylate - Names and Identifiers
Name | 1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester
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Synonyms | 1-N-Ethoxycarbonyl-indazole-5-boronic acid pinacol ester 3-(Ethoxycarbonyl)-1H-indazole-5-boronicacid,pinacolester Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-3-carboxylate 1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester 1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester
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CAS | 947191-19-7
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Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-3-carboxylate - Physico-chemical Properties
Molecular Formula | C16H21BN2O4
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Molar Mass | 316.16 |
Storage Condition | 2-8°C |
Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-3-carboxylate - Introduction
1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester is an organic compound with the chemical formula C16H19BN2O4.
Nature:
1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester is a white to pale yellow solid with a distinctive indazole aroma. It is stable at room temperature and has good solubility.
Use:
1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester has a wide range of applications in the field of medicine. It can be used as an intermediate in the synthesis of aromatic heterocyclic compounds, and can be used in the preparation of indazole anti-tumor, antibacterial and antiviral drugs.
Preparation Method:
The preparation of 1H-Indazole-3-carboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester is generally carried out by chemical reaction. A common method is the condensation of 5-indazole-6-boronate with ethyl 3-carboxylate under basic conditions to give the desired product.
Safety Information:
During storage and use, care should be taken to avoid contact with strong oxidants to prevent combustion or explosion. In addition, avoid inhalation or contact with skin and eyes, and wear appropriate protective equipment during operation.
It should be noted that the above information is for reference only. In practical application, it is also necessary to carry out detailed experimental operation and safety assessment in combination with specific conditions.
Last Update:2024-04-09 20:52:54